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Adipogen
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Image Search Results
Journal: Journal of Biological Engineering
Article Title: Integration of TLR7/8 agonists into lipid nanoparticles enhances antigen-specific immune responses to N1-methyl-Ψ-modified mRNA-LNP vaccines
doi: 10.1186/s13036-025-00573-1
Figure Lengend Snippet: Physicochemical characterization of mRNA-lipid nanoparticles with variable toll-like receptor 7/8 agonist incorporation. ( A ) Scheme summarizes the composition of various lipid nanoparticles (LNPs) and the physicochemical characterization of mRNA-LNPs using dynamic light scattering (DLS) and RiboGreen assays. ( B ) Encapsulation efficiency (EE%) was determined using the RiboGreen assay by comparing the fluorescence of free mRNA and total mRNA. ( C ) Size, polydispersity index (PDI), and zeta potential of mRNA-LNPs were measured using DLS. Each formulation was analyzed in triplicate. ( D ) Size distributions with peak diameters centered around 100–110 nm. ( B , C ) Data are shown as mean ± standard deviation
Article Snippet: Control lipid nanoparticles were formulated with the
Techniques: Encapsulation, Fluorescence, Zeta Potential Analyzer, Formulation, Standard Deviation